Harnessing Stem Cell Potential for Regenerative Medicine and Cell-Based Therapy

Abstract

Stem cell-based therapies are thought of as among the most promising new combative strategies against various developmental, traumatic, oncogenic and degenerative, including neurodegenerative, diseases. The progress, in the field of stem cell research, was made on the basis of multiple research initiatives, such as finding out the location of resident stem cells in the animal body, their isolation, in vitro culture and propagation, lineage and trans-lineage differentiation, multi-pronged experimentation both in vitro as well as in a dazzling array of animal models. While the hope for stem cell-based regenerative medicine grows by leaps and bounds, it is becoming explicitly clear from multiple pre-clinical and clinical trials that we still need greater insight and understanding of the fundamentals of stem cell biology as well as the underlying mechanism of disease in order to devise an efficient, efficacious, safe, reliable, scalable, pragmatic, cost-effective, accessible and affordable cell-based therapy.